Novel erythropoiesis stimulating protein exerts an effect on platelet function in uremia equivalent to that exerted by recombinant human erythropoietin.

CBC data for diagnosing classical megaloblastic anemia. Other features such as pancytopenia, elevated RDW, serum LDH and indirect bilirubin, as well as LDH1>LDH2 are also helpful. If a patient has a normal or low MCV, megaloblastic anemia is not usually the first consideration, which might lead to a missed diagnosis or delay in giving treatment. The present study shows that the combined disease is not difficult to diagnose when all features of megaloblastic anemia except a normal MCV are present. Other features including the RDW, WBC and platelet count, total and direct bilirubin, elevated LDH with LDH1>LDH2, decreased vitamin levels were similar to those in the patients with uncomplicated megaloblastic anemia. When we compared the parameters between groups, we found that group A was more similar to group B than to group C. Thus, a patient with combined megaloblastic anemia and thalassemia may tend to manifest megaloblastic anemia rather than thalassemia. As only MCV was different between the uncomplicated and the complicated megaloblastic anemia, megaloblastic anemia combined with thalassemia is still an easily diagnosed disease provided the clinician is alert to the possibility of this kind of disease.